Ren-Shan Ge Selected Research

Cholesterol Side-Chain Cleavage Enzyme (CYP11A1)

10/2021	Effects of bis(2-butoxyethyl) phthalate exposure in utero on the development of fetal Leydig cells in rats.
5/2021	Exposure to 4-bromodiphenyl ether during pregnancy blocks testis development in male rat fetuses.
5/2021	Low dose of fire retardant, 2,2',4,4'-tetrabromodiphenyl ether (BDE47), stimulates the proliferation and differentiation of progenitor Leydig cells of male rats during prepuberty.
1/2021	Exposure to di-n-octyl phthalate during puberty induces hypergonadotropic hypogonadism caused by Leydig cell hyperplasia but reduced steroidogenic function in male rats.
1/2021	Perfluoroheptanoic acid induces Leydig cell hyperplasia but inhibits spermatogenesis in rats after pubertal exposure.

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Ren-Shan Ge Research Topics

Disease

20	Body Weight (Weight, Body) 05/2022 - 01/2003
5	Prostatic Neoplasms (Prostate Cancer) 03/2019 - 05/2009
4	Hyperplasia 05/2021 - 10/2020
4	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2018 - 01/2010
3	Neoplasms (Cancer) 01/2022 - 03/2016
3	Hypogonadism (Hypergonadotropic Hypogonadism) 01/2021 - 10/2017
3	Fetal Growth Retardation (Intrauterine Growth Retardation) 11/2020 - 03/2016
3	Infertility (Sterility) 01/2020 - 01/2017
3	Cryptorchidism (Undescended Testes) 01/2019 - 03/2007
2	Mycoses (Diseases, Fungus) 10/2021 - 01/2017
2	Male Infertility (Male Sterility) 05/2021 - 01/2020
2	Delayed Puberty 01/2020 - 12/2018
2	Hypospadias 01/2019 - 03/2007
2	Precocious Puberty 10/2018 - 06/2018
2	Testicular Neoplasms (Testicular Cancer) 04/2007 - 03/2007
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2022
1	Carcinogenesis 01/2022
1	Neoplasm Metastasis (Metastasis) 01/2022
1	Stomach Neoplasms (Stomach Cancer) 01/2022
1	Hypoxia (Hypoxemia) 05/2021
1	Asthenozoospermia 05/2021
1	Pneumonia (Pneumonitis) 03/2021
1	Infarction (Infarctions) 02/2021
1	Feminization 02/2021
1	Hypertrophy 02/2021
1	Edema (Dropsy) 02/2021
1	Alcoholic Fatty Liver 01/2021
1	Non-alcoholic Fatty Liver Disease 01/2021
1	Myocardial Ischemia (Ischemic Heart Diseases) 01/2020
1	Arrest of spermatogenesis 09/2019

Drug/Important Bio-Agent (IBA)

11	Testosterone (Sustanon)FDA Link 10/2021 - 07/2007
8	AndrogensIBA 03/2019 - 07/2007
6	Oxidoreductases (Dehydrogenase)IBA 01/2021 - 01/2013
6	GlucocorticoidsIBA 01/2021 - 09/2008
5	Cholesterol Side-Chain Cleavage Enzyme (CYP11A1)IBA 10/2021 - 01/2021
5	EnzymesIBA 01/2021 - 05/2009
4	GossypolIBA 03/2019 - 02/2009
3	Proteins (Proteins, Gene)FDA Link 06/2021 - 03/2021
3	Corn Oil (Oil, Corn)IBA 01/2021 - 01/2018
3	CorticosteroneIBA 01/2018 - 02/2009
2	ethylene dimethanesulfonateIBA 12/2021 - 05/2019
2	triadimefon (triadimenol)IBA 10/2021 - 01/2017
2	perfluorotridecanoic acidIBA 06/2021 - 01/2021
2	Ziram (Zinc Dimethyldithiocarbamate)IBA 05/2021 - 12/2018
2	Endocrine DisruptorsIBA 05/2021 - 10/2018
2	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2021 - 07/2011
2	Estradiol (Delestrogen)FDA LinkGeneric 01/2021 - 03/2016
2	Insulin (Novolin)FDA Link 01/2021 - 01/2019
2	tebuconazoleIBA 01/2021 - 01/2017
2	vinclozolinIBA 10/2020 - 01/2017
2	Sirtuin 1IBA 10/2020 - 12/2018
2	triphenyltin (triphenyltin hydride)IBA 03/2020 - 11/2018
2	Protein Isoforms (Isoforms)IBA 01/2018 - 04/2010
2	ApigeninIBA 01/2018 - 06/2016
2	perfluorooctaneIBA 01/2017 - 03/2016
2	CurcuminIBA 11/2014 - 01/2013
2	Diethylhexyl Phthalate (DEHP)IBA 05/2009 - 07/2007
2	tyramine-deoxysorbitolIBA 04/2007 - 03/2007
1	N- fluorenylmethyloxycarbonyl- ((carboxyethyl- 2,4- dimethoxyphenyl)- 4'- methoxyphenyl)methylamineIBA 05/2022
1	Biological ProductsIBA 01/2022
1	Biomarkers (Surrogate Marker)IBA 01/2022
1	Circular RNAIBA 01/2022
1	Antifungal AgentsIBA 10/2021
1	Beclin-1IBA 05/2021
1	RNA (Ribonucleic Acid)IBA 05/2021
1	Proliferating Cell Nuclear Antigen (PCNA)IBA 05/2021
1	Interleukin-18 (Interleukin 18)IBA 03/2021
1	InflammasomesIBA 03/2021
1	CytokinesIBA 03/2021
1	IronIBA 02/2021
1	Cytochrome P-450 CYP1A1 (CYP1A1)IBA 02/2021
1	FibrinIBA 02/2021
1	di-n-octyl phthalateIBA 01/2021
1	Cortisone FDA Link 01/2021
1	piperidine-ethyl-selenopheneIBA 01/2021
1	Triglycerides (Triacylglycerol)IBA 01/2021
1	perfluoro-n-heptanoic acidIBA 01/2021
1	cyclopentanoneIBA 01/2021
1	LDL Lipoproteins (beta Lipoproteins)IBA 01/2021
1	CholesterolIBA 01/2021
1	Follicle Stimulating Hormone (Follitropin)FDA Link 01/2021
1	Luteinizing Hormone (Lutropin)FDA LinkGeneric 01/2021
1	ZearalenoneIBA 11/2020
1	N,N-dinitrosohomopiperazineIBA 10/2020
1	di-n-hexyl phthalateIBA 10/2020
1	Estrogens (Estrogen)FDA Link 01/2020
1	AdiponectinIBA 01/2020
1	CadmiumIBA 01/2020
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2020
1	Androgen Antagonists (Antiandrogens)IBA 01/2020
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2020
1	ParaquatIBA 09/2019
1	Hormones (Hormone)IBA 07/2019
1	9 alpha,11 alpha,15 alpha- trihydroxy- 16- phenoxy- 17,18,19,20- tetranorprosta- 4,5,13- trienoic acid (TPT)IBA 05/2019
1	Acetates (Acetic Acid Esters)FDA Link 03/2019
1	bisphenol AIBA 10/2018
1	taxifolinIBA 03/2018

Therapy/Procedure

2	Transplantation 10/2017 - 10/2017
1	Ischemic Postconditioning 01/2020
1	Intraperitoneal Injections 05/2019